FDA Approves HYZAAR(R) as First/Only Fixed-Dose Combination Hypertension Medicine to Help Prevent Stroke in Patients

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The new indication for unlock in stroke is substructure next to the sign LIFE (Losartan Intervention for Endpoint Reduction in Cardiovascular disease) examination. In March 2003, the Food and Drug Administration approved indistinguishable indication for Merck's antihypertensive drug COZAAR(R) (losartan potassium pills). HYZAAR and COZAAR be the single angiotensin II receptor blockers (ARBs) to be indicated to reduce the risk of stroke in patients with Cardiovascular disease and LVH. HYZAAR is the inflexible dose combination of COZAAR (losartan potassium) and hydrochlorothiazide. The Food and Drug Administration approved this indication for HYZAAR based on: 1) the utilization of COZAAR and hydrochlorothiazide in the study - the patients in both weapon store be coadministered hydrochlorothiazide the majority of occurrence they were on study drug (73.9percent and 72.4percent of days in the COZAAR and atenolol arms, respectively) and; 2) demo with Merck that the losartan and hydrochlorothiazide pills previously own in the LIFE study were bioequivalent to the bazaar HYZAAR pills.

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