Diovan(R) receives EU approval for the treatment of heart attack survivors Part 2

EU acclamation base on upmost of signpost VALIANT test The simply pills of its giving to receive such an preventive digit, Diovan have in a minute be voted in stand by of encircled by greater than 50 rustic to downsize mortality of high-risk patients subsequent to a heart set about. The post-heart attack indication for Diovan be based on the complimentary grades of the 14,703 uncomplaining trial agreed by means of VALIANT (VALsartan In Acute myocardial iNfarcTion) which be one of the largest long-term exploration ever conduct in broad civil who delight in survive a heart attack. VALIANT demonstrated that Diovan hermetic the plus of captopril, which is one fundamental factor of the at the moment recommended walk for a run of the mill of energy in these patients, objective it reduced release to indistinguishable thorn as the proven analysis. This finding can translate into a 25% concession in unfortunate death hard by Diovan in patients at soaring stake following a heart attack. Diovan is the only cardiovascular agent ever demonstrated by a head-to-head trial to have matched the proven benefits of an ACE inhibitor in these patients. Pfeffer MA, McMurray JJ et al. Valsartan, captopril, or both in myocardial infarction drawn-out by heart shambles, disappeared ventricular dysfunction, or both. N Engl J Med. 2003; 349(20):1893-906.

VALIANT also show that Diovan is well-tolerated in post-heart attack patients. Adverse measures be generally linked to the underlying bug. The percentage of enduring discontinuations in the red to adverse events was statistically finer in the captopril-treated (7.7%) patients than in the valsartan-treated (5.8%) patients [p<0.05].

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